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About Me:

Dr. Videlis Nduba, MD, PhD, is a centre director at the Centre for Respiratory Diseases Research, Kenya Medical Research Institute, in Nairobi, Kenya. As a medical officer from Kenya and epidemiologist trained at the school of public health at the University of Washington, Seattle, he started his career working in HIV and eventually transitioned to respiratory diseases. He has 18 years of clinical trials experience and has conducted multiple trials in tuberculosis vaccines, TB drug trials, sickle cell disease, and malaria drug trials.

Education:

YearDegreeInstitute
2008PhD
Master’s Degree in public healthUniversity of Washington
1999medical school

The center director at the Centre for Respiratory Diseases Research (CRDR), Kenya Medical Research Institute (KEMRI)

YearDepartmentPositionHospital

Dr. Videlis Nduba, MD, PhD, is a center director at the Centre for Respiratory Diseases Research, Kenya Medical Research Institute, in Nairobi, Kenya. As a medical officer from Kenya and epidemiologist trained at the school of public health at the University of Washington, Seattle, he started his career working in HIV and eventually transitioned to respiratory diseases. He has 18 years of clinical trials experience and has conducted multiple trials in tuberculosis vaccines, TB drug trials, sickle cell disease, and malaria drug trials.

Dr. Videlis’s work focusing on TB Research including developing tuberculosis epidemiological capacity to conduct phase II and III TB vaccine trials in adolescents and infants, diagnostics for infant TB, and epidemiology of TB in adolescents. He was a principal investor of a double-blind, randomised, placebo-controlled, dose-finding trial of the novel tuberculosis vaccine AERAS-402) in infants, of which Kenya was one of four countries participating in this trial.

Dr. Nduba has conducted two TB vaccine trials, one in infants and the other in adults that included bio banking protocols and extensive immunology sample collection and processing.

He has also lead a TB drug treatment trial that examined at a novel new treatment- MPaZ for shortening TB treatment from six to four months for drug sensitive TB. This research has included developing extensive networks with the TB treatment program, community networks with TB ambassadors and community health.

Publications

  1. Njagi, LN, Kaguthi, G, Mecha, JO, Hawn, TR, Nduba, V. Attenuated tuberculin skin test responses associated with Mycobacterium intracellulare sputum colonization in an adolescent TB prevalence survey in Western Kenya. Tuberculosis (Edinb). 2024;147 :102514. doi: 10.1016/j.tube.2024.102514. PubMed PMID:38723342 .
  2. White, T, Selvarajah, V, Wolfhagen-Sand, F, Svangård, N, Mohankumar, G, Fenici, P et al.. Prediction of cardiovascular risk factors from retinal fundus photographs: Validation of a deep learning algorithm in a prospective non-interventional study in Kenya. Diabetes Obes Metab. 2024; :. doi: 10.1111/dom.15587. PubMed PMID:38618987 .
  3. Horne, D, Nduba, V, Njagi, L, Murithi, W, Mwongera, Z, Logioia, G et al.. Tuberculosis Infectiousness is Associated with Distinct Clinical and Inflammatory Profiles. Res Sq. 2024; :. doi: 10.21203/rs.3.rs-3722244/v1. PubMed PMID:38328225 PubMed Central PMC10849670.
  4. Ndunda, JM, Sitati, J, Inziani, M, Achieng, RL, Achieng, J, Kennedy, L et al.. Accreditation of a molecular HIV diagnostic laboratory following the Strengthening Laboratory Management Towards Accreditation (SLMTA)-Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) approach in Kenya: an implementation science study. Pan Afr Med J. 2023;46 :60. doi: 10.11604/pamj.2023.46.60.39549. PubMed PMID:38223876 PubMed Central PMC10787130.
  5. Njagi, LN, Mecha, JO, Mureithi, MW, Otieno, LE, Nduba, V. Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity. BMC Med Genomics. 2024;17 (1):14. doi: 10.1186/s12920-023-01788-1. PubMed PMID:38184575 PubMed Central PMC10770971.

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